Cadaveric LT was performed for all these adult patients. Clinical data were obtained from the China Liver Transplant Registry and medical records. The data of patients who received LT in our hospital between January 11, 2015, and November 19, 2019, were collected and analyzed retrospectively. We present the following article following the STROBE reporting checklist (available at ). In this study, we reviewed the data of patients who received LT at our center to calculate the in-hospital mortality and analyze the main death-related factors. ( 6) reported that the overall in-hospital mortality was 6.3%, and the mortality of deceased donor LT was 13.5%.
( 5) reported that the in-hospital mortality after LT was 8.4%. The 1-year survival rate was 82% in the European Liver Transplant Registry and 87% in the Japanese registry, and the 10-year survival rate ranges from 53% to 76% in the American, European, and Japanese registries ( 2- 4).ĭespite the rapid developments in LT, in-hospital death threatens a certain percentage of recipients. With the development of medicines and the accumulation of experience, recipients’ survival rate has improved significantly since the first report of LT by Starzl et al. It can also benefit some patients with malignant tumors of the liver. Liver transplantation (LT) is the most effective treatment for patients with chronic end-stage liver disease and acute liver failure. Keywords: Liver transplantation (LT) in-hospital mortality risk factor Our study suggests that the main cause of in-hospital death is an infection, followed by primary non-function. MELD score was the independent risk factor for infectious death, and both body mass index of donors and cold ischemic time were independent risk factors of primary non-function.Ĭonclusions: In-hospital death poses a threat to certain patients undergoing LT. Pulmonary fungal infection was the main cause of infectious death. The first two causes of death were infection (34.3%) and primary non-function (15.7%). MELD score and intraoperative blood loss were determined as the two independent risk factors of in-hospital death. Factors including model for end-stage liver disease (MELD) score, Child-Pugh grading, intraoperative blood loss, and anhepatic phase were correlated with in-hospital death. Seventy patients died in the hospital after LT, and the in-hospital mortality rate was 13.2%. Modified piggyback orthotopic LT was performed for all patients. Results: A total of 529 patients who underwent cadaveric LT were enrolled in this study. The in-hospital mortality rate was calculated, and factors related to mortality, cause of death, and factors related to cause of death were analyzed by reviewing patients’ data. Methods: The data of patients who received LT in our hospital between January 11, 2015, and November 19, 2019, were obtained from the China Liver Transplant Registry and medical records. We designed this study to analyze patients’ in-hospital mortality rate after LT and the factors correlated with in-hospital death. However, in-hospital death cannot be avoided. Policy of Dealing with Allegations of Research Misconductīackground: Liver transplantation (LT) is a life-saving treatment for patients with end-stage liver disease and acute liver failure.Policy of Screening for Plagiarism Process.
0 kommentar(er)
